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Gene Expression Literature Summary
Assay
Age
Immunohistochemistry (whole mount)
3 DPC

19 matching records from 19 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Cdx2  caudal type homeobox 2   (Synonyms: Cdx-2)
Results  Reference
1J:191079 Acampora D, Di Giovannantonio LG, Simeone A, Otx2 is an intrinsic determinant of the embryonic stem cell state and is required for transition to a stable epiblast stem cell condition. Development. 2013 Jan 1;140(1):43-55
1J:238298 Acampora D, Omodei D, Petrosino G, Garofalo A, Savarese M, Nigro V, Di Giovannantonio LG, Mercadante V, Simeone A, Loss of the Otx2-Binding Site in the Nanog Promoter Affects the Integrity of Embryonic Stem Cell Subtypes and Specification of Inner Cell Mass-Derived Epiblast. Cell Rep. 2016 Jun 21;15(12):2651-64
1J:344642 de la Rosa S, Del Mar Rigual M, Vargiu P, Ortega S, Djouder N, Endogenous retroviruses shape pluripotency specification in mouse embryos. Sci Adv. 2024 Jan 26;10(4):eadk9394
1J:296989 Lim HYG, Alvarez YD, Gasnier M, Wang Y, Tetlak P, Bissiere S, Wang H, Biro M, Plachta N, Keratins are asymmetrically inherited fate determinants in the mammalian embryo. Nature. 2020 Sep;585(7825):404-409
1*J:314924 Liu Y, Sun J, Su Y, Lin J, Lv C, Mo K, Xu S, Wang S, Nuclear-localized eukaryotic translation initiation factor 1A is involved in mouse preimplantation embryo development. J Mol Histol. 2021 Oct;52(5):965-973
1J:275992 Menchero S, Rollan I, Lopez-Izquierdo A, Andreu MJ, Sainz de Aja J, Kang M, Adan J, Benedito R, Rayon T, Hadjantonakis AK, Manzanares M, Transitions in cell potency during early mouse development are driven by Notch. Elife. 2019 Apr 8;8:e42930
1*J:299155 Miao X, Sun T, Golan M, Mager J, Cui W, Loss of POLR1D results in embryonic lethality prior to blastocyst formation in mice. Mol Reprod Dev. 2020 Nov;87(11):1152-1158
1*J:147050 Nishioka N, Inoue K, Adachi K, Kiyonari H, Ota M, Ralston A, Yabuta N, Hirahara S, Stephenson RO, Ogonuki N, Makita R, Kurihara H, Morin-Kensicki EM, Nojima H, Rossant J, Nakao K, Niwa H, Sasaki H, The Hippo signaling pathway components Lats and Yap pattern Tead4 activity to distinguish mouse trophectoderm from inner cell mass. Dev Cell. 2009 Mar;16(3):398-410
1*J:130047 Nishioka N, Yamamoto S, Kiyonari H, Sato H, Sawada A, Ota M, Nakao K, Sasaki H, Tead4 is required for specification of trophectoderm in pre-implantation mouse embryos. Mech Dev. 2008 Mar-Apr;125(3-4):270-83
1J:104800 Niwa H, Toyooka Y, Shimosato D, Strumpf D, Takahashi K, Yagi R, Rossant J, Interaction between Oct3/4 and Cdx2 determines trophectoderm differentiation. Cell. 2005 Dec 2;123(5):917-29
1J:242325 Posfai E, Petropoulos S, de Barros FR, Schell JP, Jurisica I, Sandberg R, Lanner F, Rossant J, Position- and Hippo signaling-dependent plasticity during lineage segregation in the early mouse embryo. Elife. 2017 Feb 22;6:e22906
1*J:325355 Rong Y, Zhu YZ, Yu JL, Wu YW, Ji SY, Zhou Y, Jiang Y, Jin J, Fan HY, Shen L, Sha QQ, USP16-mediated histone H2A lysine-119 deubiquitination during oocyte maturation is a prerequisite for zygotic genome activation. Nucleic Acids Res. 2022 Jun 10;50(10):5599-5616
1J:336153 Skory RM, Moverley AA, Ardestani G, Alvarez Y, Domingo-Muelas A, Pomp O, Hernandez B, Tetlak P, Bissiere S, Stern CD, Sakkas D, Plachta N, The nuclear lamina couples mechanical forces to cell fate in the preimplantation embryo via actin organization. Nat Commun. 2023 May 29;14(1):3101
1*J:98502 Strumpf D, Mao CA, Yamanaka Y, Ralston A, Chawengsaksophak K, Beck F, Rossant J, Cdx2 is required for correct cell fate specification and differentiation of trophectoderm in the mouse blastocyst. Development. 2005 May;132(9):2093-102
1J:183948 Tao H, Inoue K, Kiyonari H, Bassuk AG, Axelrod JD, Sasaki H, Aizawa S, Ueno N, Nuclear localization of Prickle2 is required to establish cell polarity during early mouse embryogenesis. Dev Biol. 2012 Apr 15;364(2):138-48
1*J:326575 Tsume-Kajioka M, Kimura-Yoshida C, Mochida K, Ueda Y, Matsuo I, BET proteins are essential for the specification and maintenance of the epiblast lineage in mouse preimplantation embryos. BMC Biol. 2022 Mar 9;20(1):64
1*J:136803 Wang H, Ding T, Brown N, Yamamoto Y, Prince LS, Reese J, Paria BC, Zonula occludens-1 (ZO-1) is involved in morula to blastocyst transformation in the mouse. Dev Biol. 2008 Jun 1;318(1):112-25
1J:333394 Wu D, Dean J, RNA exosome ribonuclease DIS3 degrades Pou6f1 to promote mouse pre-implantation cell differentiation. Cell Rep. 2023 Jan 30;42(2):112047
1J:311921 Xu Y, Luo X, Fang Z, Zheng X, Zeng Y, Zhu C, Gu J, Tang F, Hu Y, Hu G, Jin Y, Li H, Transcription coactivator Cited1 acts as an inducer of trophoblast-like state from mouse embryonic stem cells through the activation of BMP signaling. Cell Death Dis. 2018 Sep 11;9(9):924

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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory